Saquon Barkley, RB, New York Giants: The second pick of the 2018 draft, Barkley finished with the league's sixth-fastest ball-carrier speed each of the last two seasons. He topped out at 21.89 miles per hour as a rookie and edged up to 21.91 mph last year, according to Next Gen Stats (NGS).
Dalvin Cook, RB, Minnesota Vikings: In 2018, Cook posted the second-fastest NGS time at 22.07 mph. Injuries limited him during his first two seasons, but he finally surpassed the 1,000-yard barrier and totaled 1,654 scrimmage yards in 2019.
Leonard Fournette, RB, Jacksonville Jaguars: Fournette maxed out at 21.38 mph last year, but he wowed the league as a rookie. His speeds of 22.05 and 21.76 mph ranked first and second, respectively, during the 2017 regular season.
Devin McCourty, S, New England Patriots: The veteran has plenty of speed left in the tank. During the 2018 season, per NGS, he reached 22.05 mph on a pick-six.
Henry Ruggs III: An incoming rookie, Ruggs recorded a 4.27-second 40-yard dash at the 2020 combine. He's not officially on a roster, sure, but he's an expected first-round draft pick.
Brandon Wilson, S, Cincinnati Bengals: While taking a kickoff 92 yards for a touchdown against the Baltimore Ravens during the 2019 season, Wilson hit 22.03 mph. He finished the year averaging an NFL-best 31.3 yards per kickoff return.
