A stunning fight, as both fighters said they wanted to register a knockout since the first three fights were close decisions.
Pacquiao got knocked down by a hard overhand right in the third round. That punch hurt Pacquiao, but he got up like a champion.
Pacquiao registered his own knockdown in the fifth round when he hit Marquez with a straight left that caused the Mexican to lose his balance. Pacquiao followed up with a series of hard punches, and he appeared to break Marquez's nose.
In the sixth round, Pacquiao continued to hit his opponent with hard punches, and Marquez was bloody and swollen. Pacquiao was swarming his man and it appeared he would have a big advantage in the round, possibly by a 10-8 score on the judges' scorecards.
However, in the final seconds, Pacquiao was vulnerable and in range of Marquez's big right hand. Marquez saw the opening and delivered a tremendous shot that caught Pacquiao hard on the chin.
He went down face first and was counted out. It was a knockout loss for Pacquiao at 2:59 of the sixth round.
Pacquiao had fought like a warrior and looked like a win was within his grasp, but one punch turned out his lights.
Marquez earned his first victory in the epic series.
